Involvement of TLR2 and TLR4 and Th1/Th2 shift in inflammatory responses induced by fine ambient particulate matter in mice

C Zhao, J Liao, W Chu, S Wang, T Yang, Y Tao… - Inhalation …, 2012 - Taylor & Francis
… PM2.5 in mice can lead to acute inflammatory response locally and systemically. TLR2 and
TLR4 are involved in the process of inflammation, and they induce different effects in different …

Ambient fine particulate matter induces inflammatory responses of vascular endothelial cells through activating TLR-mediated pathway

Y Le, X Hu, J Zhu, C Wang… - … and Industrial Health, 2019 - journals.sagepub.com
role of Toll-like receptors (TLRs) on fine particulate matter (PM 2.5 )-induced inflammatory
responses … We found that the mRNA levels of TLR2, TLR4, and MyD88 in the mouse aortas of …

The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter

R Miyata, SF van Eeden - Toxicology and applied pharmacology, 2011 - Elsevier
… -induced TLR4-mediated inflammatory response (TNF-α and IL-6 levels) and NF-κB activation
as elicited by comparison with SR-A−/− miceTh1/Th2 responses induced by macrophages …

Biological effects of airborne fine particulate matter (PM2. 5) exposure on pulmonary immune system

T Wei, M Tang - Environmental toxicology and pharmacology, 2018 - Elsevier
… PM 2.5 can induce local or systematic inflammatory responses. This … of rats. The variation of
cytokines illustrated that the balance of … on the shift of Th1/Th2 mediated responses are both …

TLR2 and TLR4 as potential biomarkers of environmental particulate matter exposed human myeloid dendritic cells

MA Williams, C Cheadle, T Watkins… - Biomarker …, 2007 - journals.sagepub.com
particulate matter exposed DC directed a complex Th1/Th2-like … mice to inhaled airborne
environmental particulate matter (PM10… exhaust particles provoke an inflammatory response in …

Health effects of ambient particulate matter—biological mechanisms and inflammatory responses to in vitro and in vivo particle exposures

KL Maier, F Alessandrini, I Beck-Speier… - Inhalation …, 2008 - Taylor & Francis
… 24 h in nonsensitized mice induced no significant alterations in … differential expression of
Th1/Th2 associated chemoattractants … with LPS-induced TLR2-and TLR4 responses amplify the …

Effects on IL-1β signaling activation induced by water and organic extracts of fine particulate matter (PM2. 5) in vitro

F Xu, X Qiu, X Hu, Y Shang, M Pardo, Y Fang… - Environmental …, 2018 - Elsevier
… stress and inflammatory responses were induced following … To do this, we employed
mouse macrophages to investigate the … Our study highlights the importance of the TLR4/NF-κB …

Elevated expression of miR-146, miR-139 and miR-340 involved in regulating Th1/Th2 balance with acute exposure of fine particulate matter in mice

T Hou, J Liao, C Zhang, C Sun, X Li, G Wang - International …, 2018 - Elsevier
particulate matter manifest not only inflammatory cell infiltration, but also accompanying change
… that exposure to ambient particulate matter can induce pro-inflammation release and Th1…

[HTML][HTML] … particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c mice

L Pang, P Yu, X Liu, Y Fan… - Molecular medicine …, 2021 - spandidos-publications.com
inflammation response, especially in the asthmatic mouse … imbalance in Th1/Th2, has been
reported to be involved in … )2/TLR4/myeloid differentiation primary response protein M2yD88 …

[HTML][HTML] The acute airway inflammation induced by PM2.5 exposure and the treatment of essential oils in Balb/c mice

H Wang, L Song, W Ju, X Wang, L Dong, Y Zhang… - Scientific Reports, 2017 - nature.com
… PM 2.5 (particulate matter with an aerodynamic diameter no more … in many kinds of lung
inflammatory reactions induced by viruses, … Our results of TLR4 and related genes revealed that …